A fictionalized life of the markswoman known as "Little Sure Shot," it's the story of backwoods girl whose remarkable skill with the rifle makes her the star of the flamboyant Buffalo Bill's Wild West Show. The rivalry between Annie and fellow sharpshooter Toby Walker (Preston Foster) turns to love, and Annie also develops a strong friendship with another member of the troupe, Chief Sitting Bull. The star was Barbara Stanwyck, an established leading lady with a string of successful films for such directors as Frank Capra and William Wellman. But Stanwyck had been unhappy with her recent films at Warner Brothers, and was once again freelancing. Annie Oakley was her first film for RKO, and her first-ever western.